ACADSB ELISA Kit for Human(Homo sapiens) | EIAab.comACADSB ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ACADSB(Gene name) > Human

ACADSB (Gene name),

Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (Protein name ), ACDSB_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ACADSB;

Protein name:

Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial(SBCAD);

Alternative:

2-methylbutyryl-coenzyme A dehydrogenase(2-methylbutyryl-CoA dehydrogenase);2-methyl branched chain acyl-CoA dehydrogenase(2-MEBCAD);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotetramer.

Function:

Has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.

Subcellular Location:

Mitochondrion matrix

Protein Attributes:

Sequence length:

432

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

432:

EKYFRDAKIG | TIYEGASNIQ | LNTIAKHIDA | EY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P45954

UniGene:

Hs.81934

MIM:

600301

Pfam:

PF00441

String:

P45954

KEGG:

hsa:36

STRING:

9606.ENSP00000357873

Uniprot:

P45954

FOR

ELISA Kit for Human SBCAD

Cat.:

E12556b

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Packing:

96T

ELISA Kit for Human SBCAD

Cat.:

E12556r

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96T

ELISA Kit for Human SBCAD

Cat.:

E12556m

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96T

ELISA Kit for Human SBCAD

Cat.:

E12556h

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96T

CLIA Kit for Human SBCAD

Cat.:

U12556h

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96T

CLIA Kit for Human SBCAD

Cat.:

U12556m

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96T

CLIA Kit for Human SBCAD

Cat.:

U12556r

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96T

CLIA Kit for Human SBCAD

Cat.:

U12556b

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96T

Polyclonal Antibody for Human SBCAD

Cat.:

P12556Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human SBCAD

Cat.:

P12556Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human SBCAD

Cat.:

P12556Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human SBCAD

Monoclonal Antibody for Human SBCAD

Protein for Human SBCAD

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Isolation and expression of a cDNA encoding the precursor for a novel member (ACADSB) of the acyl-CoA dehydrogenase gene family."
Rozen R. , Vockley J. , Zhou L. , Milos R. , Willard J. , Fu K. , Vicanek C. , Low-Nang L. , Torban E. , Fournier B.
Genomics24:280-287(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
2.

"Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism."
Andresen B.S. , Christensen E. , Corydon T.J. , Bross P. , Pilgaard B. , Wanders R.J.A. , Ruiter J.P.N. , Simonsen H. , Winter V. , Knudsen I. , Schroeder L.D. , Gregersen N. , Skovby F.
Am. J. Hum. Genet.67:1095-1103(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Esophagus.
tissue: Mammary gland.
4.

"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT LYS-13
tissue: Mammary gland.
7.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 6-432 (ISOFORM 1);VARIANTS LYS-13 AND VAL-316
tissue: Skeletal muscle.
8.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-284;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Crystal structure of human short-branched chain acyl-CoA dehydrogenase."
Structural genomics consortium (SGC)
Submitted (2009-02) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 52-432 IN COMPLEX WITH FAD AND SUBSTRATE ANALOG;COFACTOR;SUBUNIT
11.

"2-methylbutyryl-coenzyme A dehydrogenase deficiency: a new inborn error of L-isoleucine metabolism."
Gibson K.M. , Burlingame T.G. , Hogema B. , Jakobs C. , Schutgens R.B.H. , Millington D. , Roe C.R. , Roe D.S. , Sweetman L. , Steiner R.D. , Linck L. , Pohowalla P. , Sacks M. , Kiss D. , Rinaldo P. , Vockley J.
Pediatr. Res.47:830-833(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SBCADD PHE-255
12.

"Short/branched-chain acyl-CoA dehydrogenase deficiency due to an IVS3+3A>G mutation that causes exon skipping."
Madsen P.P. , Kibaek M. , Roca X. , Sachidanandam R. , Krainer A.R. , Christensen E. , Steiner R.D. , Gibson K.M. , Corydon T.J. , Knudsen I. , Wanders R.J. , Ruiter J.P.N. , Gregersen N. , Andresen B.S.
Hum. Genet.118:680-690(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SBCADD PHE-255

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